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Article

Iron superoxide dismutases targeted to the glycosomes of Leishmania chagasi are important for survival.

Infection and immunity - 1 Oct 2003

Plewes Katherine A, Barr Stephen D, Gedamu Lashitew

Abstract excerpt

Kinetoplastid glycosomes contain a variety of metabolic activities, such as glycolysis, beta-oxidation of fatty acids, lipid biosynthesis, and purine salvage. One advantage of sequestering metabolic activities is the avoidance of cellular oxidative damage by reactive oxygen species produced as a by-product of metabolism. Little is known about how glycosomes themselves withstand these toxic metabolites. We...

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Identifiers

PMID: 14500512
DOI: 10.1128/IAI.71.10.5910-5920.2003
PMCID: PMC201062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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