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Peroxiredoxins in Parasites

18 Nov 2011

Abstract excerpt

SIGNIFICANCE: Parasite survival and virulence relies on effective defenses against reactive oxygen and nitrogen species produced by the host immune system. Peroxiredoxins (Prxs) are ubiquitous enzymes now thought to be central to such defenses and, as such, have potential value as drug targets and vaccine antigens. RECENT ADVANCES: Plasmodial and kinetoplastid Prx systems are the most extensively studied, yet...

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PMID: 22098136
DOI: 10.1089/ars.2011.4404

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