Article
Allelic losses at chromosome 17p in human renal cell carcinoma are inversely related to allelic losses at chromosome 3p.
Cancer research - 1 Apr 1992
Ogawa O, Habuchi T, Kakehi Y, Koshiba M, Sugiyama T, Yoshida O
Abstract excerpt
Recent studies have demonstrated that allelic losses at chromosome 17p are associated with the genesis of a wide variety of human cancers. In order to assess whether the rearrangement of chromosome 17p was responsible for the genesis of renal cell carcinoma (RCC), we used restriction fragment length polymorphism analysis of chromosome 17p. We studied 48 RCCs, including 6 metastatic RCCs, from 43 patients with 5...
Topics
- Alleles
- Carcinoma, Renal Cell
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 3
- DNA Restriction Enzymes
- Heterozygote
- Humans
- Kidney Neoplasms
- Neoplasm Metastasis
