Article
Allelic loss of chromosome 17p distinguishes high grade from low grade transitional cell carcinomas of the bladder.
Cancer research - 1 Nov 1990
Olumi A F, Tsai Y C, Nichols P W, Skinner D G, Cain D R, Bender L I, Jones P A
Abstract excerpt
Forty-three transitional cell carcinomas of the bladder of differing grades and stages were examined for reduction to homozygosity for chromosomes 9q, 11p, and 17p. Allelic loss of chromosome 9q was seen in 24 of 38 informative grades II, III, and IV tumors providing further evidence for a bladder tumor suppressor gene on this chromosome. In contrast to the grade-independent involvement of chromosome 9q, allelic...
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