Article
T-cell-receptor isoforms.
International journal of cancer. Supplement = Journal international du cancer. Supplement - 1 Jan 1992
Clayton L K, Lerner A, Diener A C, Hussey R E, Koyasu S, Reinherz E L
Abstract excerpt
Early work on T-cell hybridomas lacking the T-cell-receptor (TCR) sub-unit CD3 eta had suggested a correlation between the presence of CD3 zeta-eta heterodimers and signalling leading to phosphatidyl-inositol (PI) turnover as well as activation-induced cell death. The cloning of CD3 eta has now allowed thorough and direct analysis of the signal transduction properties of CD3 zeta-zeta-, CD3 zeta-eta- and CD3...
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