Article
Amino acids important in enzyme activity and dimer stability for Drosophila alcohol dehydrogenase.
The Biochemical journal - 1 Jun 1995
Chenevert S W, Fossett N G, Chang S H, Tsigelny I, Baker M E, Lee W R
Abstract excerpt
We have determined the nucleotide sequences of eight ethyl methanesulphonate-induced mutants in Drosophila alcohol dehydrogenase (ADH), of which six were previously characterized by Hollocher and Place [(1988) Genetics 116, 253-263 and 265-274]. Four of these ADH mutants contain a single amino ac...
Topics
- Alcohol Dehydrogenase
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Drosophila melanogaster
- Genetic Complementation Test
- Macromolecular Substances
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Protein Structure, Secondary
- Protein Structure, Tertiary
- Structure-Activity Relationship