Article
RNA folding in Drosophila shows a distance effect for compensatory fitness interactions.
Genetics - 1 Sept 1993
Stephan W, Kirby D A
Abstract excerpt
Phylogenetic-comparative analysis was used to construct a secondary structure of Adh precursor messenger RNA (pre-mRNA) in Drosophila. The analysis revealed that the rate of coevolution of base-pairing residues decreases with their physical distance. This result is in qualitative agreement with a...
Topics
- Alcohol Dehydrogenase
- Animals
- Base Sequence
- Biological Evolution
- Drosophila
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Phylogeny
- RNA Precursors
- RNA, Messenger