Article
Deletion of chromosome 11p13-11p15.5 sequences in invasive human ovarian cancer is a subclonal progression factor.
Cancer research - 1 Dec 1992
Vandamme B, Lissens W, Amfo K, De Sutter P, Bourgain C, Vamos E, De Grève J
Abstract excerpt
In human ovarian cancer, multiple specific chromosomal deletions can be found by cytogenetic analysis or molecular techniques such as restriction fragment length polymorphism probing. This work confirms the loss of HRAS alleles in 1 out of 2 cases of invasive ovarian cancer as determined in 32 samples or cell lines derived from 19 patients. Results with other polymorphic probes indicate that a consensus deletion...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.