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Article

Amplification of 11q13 in ovarian carcinoma

3 Mar 2008

Abstract excerpt

Amplification at the 11q13 locus is commonly observed in breast, ovarian, head and neck, oral, and esophageal cancer. Studies of this region led to the identification of multiple amplicons containing several potential oncogenes including EMSY, PAK1, RSF1, and GAB2. Here, we investigate the amplification of the above four genes and their prognostic significance in histologically and clinically defined subsets of...

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Share to Cancer Genomics and Diagnostics
Share to Genomic variations and chromosomal abnormalities
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PMID: 18314909
DOI: 10.1002/gcc.20549

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