Article
Mutations in the p53 gene in radiation-sensitive and -resistant human squamous carcinoma cells.
Cancer research - 15 Nov 1992
Jung M, Notario V, Dritschilo A
Abstract excerpt
Five of six human squamous cell carcinoma (SCC) cell lines characterized as radiation sensitive (SQ-38, SCC-9, SQ-9G) or radiation resistant (SQ-20B, SCC-35, JSQ-3) exhibited alterations of the p53 gene. The point mutations and a deletion were detected by using single-stranded conformational polymorphism analysis and polymerase chain reaction-direct sequencing. Interestingly, three of three radiation-sensitive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
