Article
Infrequent alterations of the p53 gene in rat skin cancers induced by ionizing radiation.
Carcinogenesis - 1 Apr 1996
Jin Y, Burns J, Garte S J, Hosselet S
Abstract excerpt
Radiation carcinogenesis almost certainly involves multiple genetic alterations. Identification of such genetic alterations would provide information to help understand better the molecular mechanism of radiation carcinogenesis. The energy released by ionizing radiation has the potential to produce DNA strand breaks, major gene deletions or rearrangements, and other base damages. Alterations of the p53 gene, a...
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