Article
Cross-resistance to meropenem, cephems, and quinolones in Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy - 1 Sept 1992
Masuda N, Ohya S
Abstract excerpt
Multiple-drug-resistant mutants were isolated from Pseudomonas aeruginosa PAO1 on agar plates containing ofloxacin and cefsulodin. These mutants were four to eight times more resistant to meropenem, cephems, carbenicillin, quinolones, tetracycline, and chloramphenicol than the parent strain was. In contrast, these mutants showed no significant changes in their susceptibilities to all carbapenems except meropenem....
Topics
- Anti-Bacterial Agents
- Anti-Infective Agents
- Bacterial Outer Membrane Proteins
- Bacteriophages
- Cefsulodin
- Drug Resistance, Microbial
- Electrophoresis, Polyacrylamide Gel
- Meropenem
- Microbial Sensitivity Tests
- Mutation
- Ofloxacin