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Article

Resistance mechanisms of multiresistant Pseudomonas aeruginosa strains from Germany and correlation with hypermutation.

Antimicrobial agents and chemotherapy - 1 Nov 2007

Henrichfreise B, Wiegand I, Pfister W, Wiedemann B

Abstract excerpt

In this study, we analyzed the mechanisms of multiresistance for 22 clinical multiresistant and clonally different Pseudomonas aeruginosa strains from Germany. Twelve and 10 strains originated from cystic fibrosis (CF) and non-CF patients, respectively. Overproduction of the efflux systems MexAB-OprM, MexCD-OprJ, MexEF-OprN, and MexXY-OprM was studied. Furthermore, loss of OprD, alterations in type II...

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Identifiers

PMID: 17876002
DOI: 10.1128/AAC.00148-07
PMCID: PMC2151423

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Source receipt: pubmed, retrieved 7 Sept 2026.

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