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Article

Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump.

Antimicrobial agents and chemotherapy - 1 Jul 2008

Jeannot Katy, Elsen Sylvie, Köhler Thilo, Attree Ina, van Delden Christian, Plésiat Patrick

Abstract excerpt

Since their initial description 2 decades ago, MexCD-OprJ-overproducing efflux mutants of Pseudomonas aeruginosa (also called nfxB mutants) have rarely been described in the clinical setting. Screening of 110 nonreplicate clinical isolates showing moderate resistance to ciprofloxacin (MIC from 0.5 microg/ml to 4 microg/ml) yielded only four mutants (3.6%) of that type harboring various alterations in the...

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Identifiers

PMID: 18474583
DOI: 10.1128/AAC.01107-07
PMCID: PMC2443911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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