Article
Significant linkage disequilibrium between the Huntington disease gene and the loci D4S10 and D4S95 in the Dutch population.
American journal of human genetics - 1 Oct 1992
Skraastad M I, Van de Vosse E, Belfroid R, Höld K, Vegter-van der Vlis M, Sandkuijl L A, Bakker E, van Ommen G J
Abstract excerpt
Significant linkage disequilibrium has been found between the Huntington disease (HD) gene and DNA markers located around D4S95 and D4S98. The linkage-disequilibrium studies favor the proximal location of the HD gene, in contrast to the conflicting results of recombination analyses. We have analy...
Topics
- Alleles
- DNA
- Genetic Linkage
- Genetic Markers
- Haplotypes
- Humans
- Huntington Disease
- Netherlands
- Restriction Mapping
