The Sjögren-Larsson syndrome gene is close to D17S805 as determined by linkage analysis and allelic association.

doi:10.1038/ng1294-361

Back to search

Article

The Sjögren-Larsson syndrome gene is close to D17S805 as determined by linkage analysis and allelic association.

Nature genetics - 1 Dec 1994

Pigg M, Jagell S, Sillén A, Weissenbach J, Gustavson K H, Wadelius C

Abstract excerpt

Sjögren-Larsson Syndrome (SLS) is characterized by congenital ichthyosis, spastic dior tetraplegia and mental retardation. It is an autosomal recessive trait that is frequent in the northern part of Sweden. Based on linkage analysis and allelic association, the disorder has now been mapped to chr...

Topics

Alleles
Chromosome Mapping
Chromosomes, Artificial, Yeast
Chromosomes, Human, Pair 17
Female
Genetic Linkage
Haplotypes
Humans
Male
Meiosis
Pedigree
Recombination, Genetic
Sjogren-Larsson Syndrome

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.