Article
Allele frequencies and linkage disequilibrium of polymorphic DNA markers of the Huntington disease region in the German population.
Human genetics - 1 Dec 1993
Thies U, Bockel B, Gerdes B, Schröder K
Abstract excerpt
Allele frequencies of 14 different restriction fragment length polymorphisms from 12 DNA markers within the Huntington disease (HD) region were evaluated in the German population. No significant differences from published data of allele frequencies from chromosomes of Caucasian ancestry were found. The analysis of eight DNA polymorphisms in 87 HD families of German origin revealed significant non-random...
Topics
- Alleles
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 4
- DNA
- Electrophoresis, Agar Gel
- Gene Frequency
- Genetic Markers
- Germany
- Humans
- Huntington Disease
