Article
Genetic linkage between Huntington disease and the D4S10 locus in South African families: further evidence against non-allelic heterogeneity.
Human genetics - 1 Oct 1991
Greenberg L J, Martell R W, Theilman J, Hayden M R, Joubert J
Abstract excerpt
A study of genetic linkage between Huntington disease (HD) and the D4S10 locus (G8) has been undertaken in 10 South African (SA) families originating from the black, white and mixed acestry population groups. Allele frequencies at the D4S10 locus have been established in the non-Caucasoid population groups. There are significant differences in the allele frequencies at the D4S10 locus between the various SA...
Topics
- Alleles
- Black People
- Chromosomes, Human, Pair 4
- Female
- Gene Frequency
- Genetic Linkage
- Genetic Markers
- Haplotypes
- Heterozygote
- Humans
- Huntington Disease