Article
Thromboxane augmentation of alloreactive T cell function.
Transplantation - 1 Sept 1992
Ruiz P, Rey L, Spurney R, Coffman T, Viciana A
Abstract excerpt
Thromboxane (Tx) plays a vital role in the dysfunction and ultimate rejection of MHC-disparate renal allografts. In addition to its potent vasoconstrictory properties, in vivo studies have implied that Tx is capable of promoting immune cytotoxic T cell function within transplants. In this study, we have examined the in vitro effect of Tx inhibition on alloreactive immune cells using MHC-disparate mouse strain...
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