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Article

Mouse vascular endothelium activates CD8+ T lymphocytes in a B7-dependent fashion.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2002

Kreisel Daniel, Krupnick Alexander S, Balsara Keki R, Riha Markus, Gelman Andrew E, Popma Sicco H, Szeto Wilson Y, Turka Laurence A, Rosengard Bruce R

Abstract excerpt

Despite several studies examining the contribution of allorecognition pathways to acute and chronic rejection of vascularized murine allografts, little data describing activation of alloreactive T cells by mouse vascular endothelium exist. We have used primary cultures of resting or IFN-gamma-activated C57BL/6 (H-2(b)) vascular endothelial cells as stimulators and CD8(+) T lymphocytes isolated from CBA/J (H-2(k))...

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PMID: 12444119
DOI: 10.4049/jimmunol.169.11.6154

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APC
CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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