Article
The effect of A2A adenosine receptor agonist on composite tissue allotransplant survival: an in vivo preliminary study.
The Journal of surgical research - 1 Apr 2006
Ulusal Betul Gozel, Ulusal Ali Engin, Hung Li-Man, Wei Fu-Chan
Abstract excerpt
BACKGROUND: In vitro experimental studies showed that A2a receptor agonists reduce allostimulatory functions of the dendritic cells through modulation of surface expression of the costimulatory molecules and down-regulation of cytokines. Similar suppressive effects on dendritic cells have also been observed with Cyclosporine A (CsA). In this study we sought to explore if combined use of these two drugs in vivo...
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