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Article

Translational readthrough at nonsense mutations in the HSF1 gene of Saccharomyces cerevisiae.

Molecular & general genetics : MGG - 1 Sept 1992

Kopczynski J B, Raff A C, Bonner J J

Abstract excerpt

The HSF1 gene of Saccharomyces cerevisiae directs the synthesis of the heat shock transcription factor, HSF. The gene is essential; disruption mutations are lethal. Using a plasmid shuffle screen, we isolated mutations in the HSF1 gene after in vitro mutagenesis of plasmid DNA with hydroxylamine. From a collection of both conditional (temperature-sensitive) and unconditional lethal mutations, we recovered...

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Source

Identifiers

PMID: 1406583
DOI: 10.1007/BF00538696

Genes

HSF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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