Article
Mutations in the Schizosaccharomyces pombe heat shock factor that differentially affect responses to heat and cadmium stress.
Molecular & general genetics : MGG - 1 Feb 1999
Saltsman K A, Prentice H L, Kingston R E
Abstract excerpt
Heat shock factor (hsf) is the transcriptional activator that governs the transcriptional response of eukaryotic cells to stressful conditions. The structure and regulation of hsf is highly conserved. We describe deletion mutations in hsf+ that alter the ability of Schizosaccharomyces pombe to respond to different stressful conditions. One mutation causes increased sensitivity to cadmium while maintaining near...
Topics
- Binding Sites
- Cadmium
- DNA-Binding Proteins
- Genes, Fungal
- HSP70 Heat-Shock Proteins
- Heat-Shock Proteins
- Hot Temperature
- Mutation
- Protein Binding
- Protein Kinases
- Repressor Proteins
- Saccharomyces cerevisiae Proteins
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins