Article
Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo.
Molecular and cellular biology - 1 Apr 1996
Sun Z W, Hampsey M
Abstract excerpt
An ssu72 mutant of Saccharomyces cerevisiae was identified as an enhancer of a TFIIB defect (sua7-1) that confers both a cold-sensitive growth defect and a downstream shift in transcription start site selection. The ssu72-1 allele did not affect cold sensitivity but, in combination with sua7-1, c...
Topics
- Amino Acid Sequence
- Base Sequence
- Enhancer Elements, Genetic
- Genes, Fungal
- Hot Temperature
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae
- Transcription Factor TFIIB
- Transcription Factors
- Transcription, Genetic