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Article

Detection of hepatitis B pre-core mutant by allele specific polymerase chain reaction.

Journal of clinical pathology - 1 Aug 1992

Lo E S, Lo Y M, Tse C H, Fleming K A

Abstract excerpt

AIM: Development of a specific polymerase chain reaction (PCR) assay for detection of the pre-core, stop codon, mutant of hepatitis B virus (HBV). METHODS: PCR primers, specific at the 3'-end for nucleotide 1896 of either the pre-core, stop codon, mutant or wild type HBV, were synthesised using published sequence data. Positive control templates for both types of virus were synthesised by the PCR, incorporating...

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Identifiers

PMID: 1401178
DOI: 10.1136/jcp.45.8.689
PMCID: PMC495145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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