Article
[Construction of a genechip method for detection of hepatitis B virus DNA, basal core promotor and Pre-C mutants].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Jun 2004
Li Bing, Peng Jin-fu, Chen Li-yan, Wang Zhao-qin, Li Li-xiong, Wang Min, Li Jiang, Zhou Bo-ping
Abstract excerpt
BACKGROUND: To establish a genechip method for detection of hepatitis B virus (HBV) DNA, basal core promotor (BCP), and Pre-C mutants. METHODS: This study used two kinds of technology (PCR, oligochip), which can detect five mutant hotspots including nt 1 896, nt 1 899, nt 1 862, nt 1 764 and nt 1 762. The results of genechip method was verified by DNA sequencing. RESULTS: In detecting HBV DNA, the results of...
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