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Article

Development of a molecular-beacon assay to detect the G1896A precore mutation in hepatitis B virus-infected individuals.

Journal of clinical microbiology - 1 Jan 2005

Waltz Therese L, Marras Salvatore, Rochford Gemma, Nolan John, Lee Eugenia, Melegari Margherita, Pollack Henry

Abstract excerpt

The 1896 precore (PC) mutation is the most frequent cause of hepatitis B virus e-antigen (HBeAg)-negative chronic hepatitis B virus (HBV) infection. Detection of the 1896 PC mutation has application in studies monitoring antiviral therapy and the natural history of the disease. Identification of this mutation is usually performed by direct sequencing, which is both costly and laborious. The aim of this study was...

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Identifiers

PMID: 15634980
DOI: 10.1128/JCM.43.1.254-258.2005
PMCID: PMC540133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Development of a molecular-beacon assay to detect the G1896A precore mutation in hepatitis B virus-infected individuals.PMID 15634980Read ↗

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