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Article

Genomic mapping within the albino-deletion complex using individual early postimplantation mouse embryos.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1992

Sharan S K, Holdener-Kenny B, Threadgill D W, Magnuson T

Abstract excerpt

Sensitive methods for analysis of DNA from limited amounts of tissue are often difficult, error prone, and time consuming. Here, we describe a procedure for molecular analysis of individual early postimplantation mouse embryos by Southern analysis. The procedure involves embedding single embryos in agarose before lysing and deproteinizing in situ. The embedded DNA can be digested with restriction enzymes and...

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PMID: 1617218
DOI: 10.1007/BF00431250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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