Article
Genomic mapping within the albino-deletion complex using individual early postimplantation mouse embryos.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1992
Sharan S K, Holdener-Kenny B, Threadgill D W, Magnuson T
Abstract excerpt
Sensitive methods for analysis of DNA from limited amounts of tissue are often difficult, error prone, and time consuming. Here, we describe a procedure for molecular analysis of individual early postimplantation mouse embryos by Southern analysis. The procedure involves embedding single embryos...
Topics
- Albinism
- Animals
- Blotting, Southern
- Chromosome Deletion
- Chromosome Mapping
- Embryonic Development
- Feasibility Studies
- Female
- Genetic Complementation Test
- Genetic Markers
- Genotype
- Homozygote
