Article
Parental chromosome-specific chromatin conformation in the imprinted U2af1-rs1 gene in the mouse.
The Journal of biological chemistry - 15 Aug 1997
Feil R, Boyano M D, Allen N D, Kelsey G
Abstract excerpt
The imprinted U2af1-rs1 gene on mouse chromosome 11 is expressed exclusively from the paternal allele. We found that U2af1-rs1 resides in a chromosomal domain that displays marked differences in chromatin conformation and DNA methylation between the parental chromosomes. Chromatin conformation was assayed in brain and liver, in fetuses, and in embryonic stem cells by sensitivity to nucleases in nuclei. In all...
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