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Autosomal and X-chromosome imprinting

1 Apr 1990

Abstract excerpt

Mouse genetic studies using Robertsonian and reciprocal translocations have shown that certain autosomal regions of loci are subject to a parental germ line imprint, which renders maternal and paternal copies functionally inequivalent in the embryo or later stages of development. Duplication of maternal or paternal copies with corresponding paternal/maternal deficiencies in chromosomally balanced zygotes causes...

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PMID: 2090432
DOI: 10.1242/dev.108.supplement.63

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