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Article

Differential regulation of imprinting in the murine embryo and placenta by the Dlk1-Dio3 imprinting control region.

Development (Cambridge, England) - 1 Jan 2007

Lin Shau-Ping, Coan Phil, da Rocha Simao Teixeira, Seitz Herve, Cavaille Jerome, Teng Pi-Wen, Takada Shuji, Ferguson-Smith Anne C

Abstract excerpt

Genomic imprinting is an epigenetic mechanism controlling parental-origin-specific gene expression. Perturbing the parental origin of the distal portion of mouse chromosome 12 causes alterations in the dosage of imprinted genes resulting in embryonic lethality and developmental abnormalities of both embryo and placenta. A 1 Mb imprinted domain identified on distal chromosome 12 contains three paternally expressed...

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PMID: 17166925
DOI: 10.1242/dev.02726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential regulation of imprinting in the murine embryo and placenta by the Dlk1-Dio3 imprinting control region.PMID 17166925Read ↗

At Least Ten Genes Define the Imprinted Dlk1-Dio3 Cluster on Mouse Chromosome 12qF1Semantic proximity Read ↗

Balanced gene dosage control rather than parental origin underpins genomic imprinting.Semantic proximity Read ↗

Epigenetic control and genomic imprinting dynamics of the Dlk1-Dio3 domainSemantic proximity Read ↗

A bipartite element with allele-specific functions safeguards DNA methylation imprints at the <i>Dlk1-Dio3</i> locusSemantic proximity Read ↗

Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain.Semantic proximity Read ↗

Methylation dynamics of IG-DMR and Gtl2-DMR during murine embryonic and placental development.Semantic proximity Read ↗

Identification and characterisation of imprinted genes in the mouse.Semantic proximity Read ↗

A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus.Semantic proximity Read ↗

Imprinting and expression analysis of a non-coding RNA gene in the mouse Dlk1-Dio3 domain.Semantic proximity Read ↗

DNA methylation dynamics of genomic imprinting in mouse development†Semantic proximity Read ↗

DLK1-DIO3 imprinted locus deregulation in development, respiratory disease, and cancer.Semantic proximity Read ↗

Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3.Semantic proximity Read ↗

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