Linkage analysis of glucokinase gene with NIDDM in Caucasian pedigrees.

doi:10.2337/diab.41.11.1496

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Article

Linkage analysis of glucokinase gene with NIDDM in Caucasian pedigrees.

Diabetes - 1 Nov 1992

Cook J T, Hattersley A T, Christopher P, Bown E, Barrow B, Patel P, Shaw J A, Cookson W O, Permutt M A, Turner R C

Abstract excerpt

NIDDM has a strong genetic component, as evidenced by the high level of concordance between identical twins. The nature of the genetic predisposition has remained largely unknown. Recently, the glucokinase gene locus on chromosome 7p has been shown to be linked to a subtype of NIDDM known as MODY...

Topics

Adult
Aged
Base Sequence
DNA
Diabetes Mellitus, Type 2
Family
Female
Genetic Linkage
Genotype
Glucokinase
Humans
Male
Middle Aged
Molecular Sequence Data
Oligodeoxyribonucleotides
Pedigree
Polymerase Chain Reaction
White People

Source

Open in PubMed

Identifiers

PMID: 1397724
DOI: 10.2337/diab.41.11.1496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1397724-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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