Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus.

Nature - 23 Apr 1992

Vionnet N, Stoffel M, Takeda J, Yasuda K, Bell G I, Zouali H, Lesage S, Velho G, Iris F, Passa P

Abstract excerpt

Maturity-onset diabetes of the young (MODY) is a form of non-insulin-dependent (type 2) diabetes mellitus (NIDDM) which is characterized by an early age at onset and an autosomal dominant mode of inheritance. Except for these features, the clinical characteristics of patients with MODY are similar to those with the more common late-onset form(s) of NIDDM. Previously we observed tight linkage between DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Probes
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Pedigree

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 1570017
DOI: 10.1038/356721a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus.PMID 1570017Read ↗

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Maturity-onset diabetes of the young.Semantic proximity Read ↗

[Glucokinase gene abnormalities in maturity-onset diabetes of the young (MODY) and late-onset NIDDM].Semantic proximity Read ↗

Linkage analysis and molecular scanning of glucokinase gene in NIDDM families.Semantic proximity Read ↗

Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus.Semantic proximity Read ↗

Maturity-onset diabetes of the young.Semantic proximity Read ↗

Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes.Semantic proximity Read ↗

Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus.Semantic proximity Read ↗

Linkage of type 2 diabetes to the glucokinase gene.Semantic proximity Read ↗

Candidate gene studies in pedigrees with maturity-onset diabetes of the young not linked with glucokinase.Semantic proximity Read ↗

A novel nonsense mutation in GCK exon 9 co-segregates with diabetes phenotype.Semantic proximity Read ↗

Search for a third susceptibility gene for maturity-onset diabetes of the young. Studies with eleven candidate genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.