Article
Candidate gene studies in pedigrees with maturity-onset diabetes of the young not linked with glucokinase.
Diabetologia - 1 Sept 1995
Zhang Y, Warren-Perry M, Saker P J, Hattersley A T, Mackie A D, Baird J D, Greenwood R H, Stoffel M, Bell G I, Turner R C
Abstract excerpt
Maturity-onset diabetes of the young (MODY) is a form of non-insulin-dependent diabetes mellitus characterised by an early age of onset and an autosomal dominant mode of inheritance. Only a proportion of cases are due to mutations in the glucokinase gene. We have studied five Caucasian MODY families, including the first MODY family to be described, with five candidate genes implicated in regulation of insulin...
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