Article
Candidate gene studies in pedigrees with maturity-onset diabetes of the young not linked with glucokinase.
Diabetologia - 1 Sept 1995
Zhang Y, Warren-Perry M, Saker P J, Hattersley A T, Mackie A D, Baird J D, Greenwood R H, Stoffel M, Bell G I, Turner R C
Abstract excerpt
Maturity-onset diabetes of the young (MODY) is a form of non-insulin-dependent diabetes mellitus characterised by an early age of onset and an autosomal dominant mode of inheritance. Only a proportion of cases are due to mutations in the glucokinase gene. We have studied five Caucasian MODY famil...
Topics
- Adolescent
- Adult
- Age Factors
- Age of Onset
- Aged
- Base Sequence
- Child
- DNA
- DNA Primers
- Diabetes Mellitus, Type 2
- Female
- Follow-Up Studies
- Genes, Dominant
- Genetic Linkage
- Genetic Markers
- Glucokinase
- Humans
- Incidence