Linkage of type 2 diabetes to the glucokinase gene.

doi:10.1016/0140-6736(92)91958-b

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Article

Linkage of type 2 diabetes to the glucokinase gene.

Lancet (London, England) - 30 May 1992

Hattersley A T, Turner R C, Permutt M A, Patel P, Tanizawa Y, Chiu K C, O'Rahilly S, Watkins P J, Wainscoat J S

Abstract excerpt

Maturity-onset diabetes of the young (MODY) is a subtype of type 2 diabetes that presents from the second decade and has an autosomal dominant mode of inheritance. We have investigated the glucokinase gene, a candidate gene for diabetes, in two MODY pedigrees. In a large 5-generation pedigree (BX...

Topics

Adolescent
Adult
Aged
Base Sequence
Blood Glucose
Child
Chromosome Mapping
Chromosomes, Human, Pair 7
DNA
Diabetes Mellitus, Type 2
Fasting
Female
Genes, Dominant
Genetic Linkage
Genetic Testing
Glucokinase
Glucose Tolerance Test
Humans

Source

Open in PubMed

Identifiers

PMID: 1349989
DOI: 10.1016/0140-6736(92)91958-b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1349989-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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