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Article

Altered conformation of the p53 protein in myeloid leukemia cells and mitogen-stimulated normal blood cells.

Oncogene - 1 Aug 1992

Zhang W, Hu G, Estey E, Hester J, Deisseroth A

Abstract excerpt

Expression of the normal p53 gene promotes cell differentiation, maturation and apoptosis. The mutant p53 gene, which does not function normally, is frequently expressed at elevated levels in tumor cells [for review see Lane, D.P. & Benchimol, S. (1990). Genes Dev., 4, 1-8]. We have analysed the expression of and mutational change in the p53 gene in the peripheral blood cells of 49 primary acute myeloid leukemia...

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Source

Identifiers

PMID: 1630824

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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