Development and significance of nucleoside drug resistance in infection caused by the human immunodeficiency virus type 1.

Article

Development and significance of nucleoside drug resistance in infection caused by the human immunodeficiency virus type 1.

Clinical and investigative medicine. Medecine clinique et experimentale - 1 Jun 1994

Smith M, Salomon H, Wainberg M A

Abstract excerpt

Nucleoside antagonists of human immunodeficiency virus (HIV) reverse transcriptase (RT) activity have been commonly used in the therapy of HIV-associated disease. The prolonged use of such drugs has led to the development of HIV variants that display resistance against these compounds. HIV drug r...

Topics

Acquired Immunodeficiency Syndrome
Antiviral Agents
Drug Resistance
HIV Reverse Transcriptase
HIV-1
Humans
Mutation
Nucleosides
Reverse Transcriptase Inhibitors

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