Article
In vivo prevalence of azidothymidine (AZT) resistance mutations in an AIDS patient before and after AZT therapy.
AIDS research and human retroviruses - 1 Mar 1991
Fitzgibbon J E, Howell R M, Schwartzer T A, Gocke D J, Dubin D T
Abstract excerpt
In order to examine the in vivo prevalence of AZT resistance mutations in AID patients after long-term therapy we amplified, by polymerase chain reaction (PCR), a 654 bp pol gene fragment from peripheral blood mononuclear cell DNA samples from a patient before, and 19 months after, the start of A...
Topics
- Acquired Immunodeficiency Syndrome
- Adult
- Amino Acid Sequence
- Base Sequence
- DNA, Viral
- Drug Resistance, Microbial
- Genes, pol
- HIV
- Humans
- Male
- Molecular Sequence Data
- Mutation