Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of amino acid sequences in the integrin beta 1 cytoplasmic domain implicated in cytoskeletal association.

The Journal of cell biology - 1 Jun 1992

Reszka A A, Hayashi Y, Horwitz A F

Abstract excerpt

Wild-type and mutant chicken integrin beta 1 subunit (beta 1c) cDNAs were expressed in NIH 3T3 cells and assayed for localization in focal adhesions of cells plated on fibronectin substrates. Focal adhesion localization in stable transfected cells was assayed by indirect immunofluorescent staining with chicken-specific anti-beta 1c antibodies. Mutant beta 1c integrins containing internal deletions of 13 amino...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3 Cells
Share to Amino Acid Sequence
Share to Cytoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique

Share to Molecular Sequence Data

Share to Mutation

Share to Sequence Alignment

Source

Open in PubMed Open full text

Identifiers

PMID: 1376731
DOI: 10.1083/jcb.117.6.1321
PMCID: PMC2289496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of amino acid sequences in the integrin beta 1 cytoplasmic domain implicated in cytoskeletal association.PMID 1376731Read ↗

NPXY motifs control the recruitment of the alpha5beta1 integrin in focal adhesions independently of the association of talin with the beta1 chain.Semantic proximity Read ↗

Mapping of the functional determinants of the integrin beta 1 cytoplasmic domain by site-directed mutagenesis.Semantic proximity Read ↗

Expression and function of chicken integrin beta 1 subunit and its cytoplasmic domain mutants in mouse NIH 3T3 cells.Semantic proximity Read ↗

Effects of mutations in the cytoplasmic domain of integrin beta(1) to talin binding and cell spreading.Semantic proximity Read ↗

Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin.Semantic proximity Read ↗

Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodiesSemantic proximity Read ↗

beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms.Semantic proximity Read ↗

beta1-integrin cytoplasmic subdomains involved in dominant negative function.Semantic proximity Read ↗

Regulation of integrin affinity states through an NPXY motif in the beta subunit cytoplasmic domain.Semantic proximity Read ↗

Epitope-specific antibodies to the beta(1C) integrin cytoplasmic domain variant.Semantic proximity Read ↗

Functional analysis of the cytoplasmic domain of the integrin {alpha}1 subunit in endothelial cells.Semantic proximity Read ↗

Cytoplasmic domain mutants of beta1 integrin, expressed in beta 1-knockout lymphoma cells, have distinct effects on adhesion, invasion and metastasis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.