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Article

Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies

1 Aug 1993

Abstract excerpt

Members of the beta 1 integrin subfamily recognize multiple ligands such as fibronectin, laminin, and collagen and mediate cell-cell and cell-extracellular matrix interactions. beta 1 subunit may play a central role in regulating beta 1 integrin avidity. Here we have identified a small region of beta 1 subunit (residues 207-218) that is critical for the binding of both activating (8A2, A1A5, and TS2/16) and...

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Identifiers

PMID: 7688727
DOI: 10.1016/s0021-9258(19)85374-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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