Article
Epitope-specific antibodies to the beta(1C) integrin cytoplasmic domain variant.
Experimental and molecular pathology - 1 Jun 2001
Fornaro M, Lovecchio M, Jose P, Zheng D Q, Moro L, Languino L R
Abstract excerpt
The beta(1C) integrin is an alternatively spliced variant of the beta(1) subunit that contains a unique 48-amino-acid sequence in its cytoplasmic domain. We have shown previously that beta(1C) is a potent inhibitor of cell proliferation and that in vivo its expression is downregulated in prostate and breast carcinoma. In this study, we describe a panel of specific monoclonal antibodies that react with the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
