Article
A comparison of induced mutation at homologous alleles of the tk locus in human cells. II. Molecular analysis of mutants.
Mutation research - 1 May 1992
Amundson S A, Liber H L
Abstract excerpt
Previously we described the dose-response relationship for X-ray-induced mutation of the two homologous alleles of the thymidine kinase (tk) gene in a human lymphoblastoid cell line (Amundson and Liber, 1991). The two alleles were differentially mutable by X-rays, with one allele 6-10 times more mutable than the other. This difference was shown to be due to the virtual absence of the class of slow growth mutants...
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