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Article

Frequency of HPRT mutants in humans exposed to vinyl chloride via an environmental accident.

Mutation research - 25 Jul 2001

Becker R, Nikolova T, Wolff I, Lovell D, Hüttner E, Foth H

Abstract excerpt

The mutant frequency (MF) in the hypoxanthine-guanine-phosphoribosyl-transferase (HPRT) locus of peripheral blood T-lymphocytes was measured in a population environmentally exposed to vinyl chloride - a toxic and carcinogenic substance through an accidental release into the atmosphere. It was compared to MF in a control group of unexposed individuals. Both groups were re-investigated in a follow-up study, 2 years...

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Source

Identifiers

PMID: 11423348
DOI: 10.1016/s1383-5718(01)00182-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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