Article
p53 status and human papillomavirus infection in Thai women with cervical carcinoma.
The Southeast Asian journal of tropical medicine and public health - 1 Mar 2000
Limpaiboon T, Pooart J, Bhattarakosol P, Niruthisard S, Chantratita W, Lulitanond V
Abstract excerpt
Loss of p53 function has been implicated in a wide variety of human malignacies. Many studies suggest that in cervical carcinoma p53 function is inactivated either by gene mutation or by complex formation with E6 oncoprotein product of high-risk human papillomavirus (HPV). The aim of this study was to determine the status of HPV infection and p53 gene mutation as well as their correlation in cervical carcinomas....
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