Article
Studies of variability in the islet amyloid polypeptide gene in relation to Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association - 1 Jun 2003
Pildal J, Lajer M, Hansen S K, Almind K, Ambye L, Borch-Johnsen K, Carstensen B, Hansen T, Pedersen O
Abstract excerpt
AIMS: To explore whether the coding region of the islet amyloid polypeptide (IAPP) gene contains genetic variants associated with Type 2 diabetes and whether a previously reported association of the promoter variant -132g-->a with Type 2 diabetes could be reproduced in Danish Caucasians. METHODS: The coding region was analyzed using single strand conformation polymorphism (SSCP) and heteroduplex analysis in 192...
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