Article
Sequence variations of the pancreatic islet/liver glucose transporter (GLUT2) gene in Japanese subjects with noninsulin dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism - 1 Nov 1995
Matsubara A, Tanizawa Y, Matsutani A, Kaneko T, Kaku K
Abstract excerpt
To assess the genetic susceptibility to noninsulin-dependent diabetes mellitus (NIDDM) in Japanese subjects, we investigated the role of GLUT2 gene defects in patients with NIDDM. When the allelic frequency of a simple tandem repeat polymorphism in the GLUT2 gene was compared, the allele with 155...
Topics
- Adult
- Alleles
- Amino Acid Sequence
- Diabetes Mellitus, Type 2
- Genes
- Genetic Variation
- Glucose Transporter Type 2
- Humans
- Introns
- Islets of Langerhans
- Japan
- Liver
- Middle Aged
- Molecular Sequence Data
- Monosaccharide Transport Proteins
- Mutation
- Pedigree
- Polymorphism, Genetic