Article
Study of HLA-DQA1 alleles in celiac children.
Journal of investigational allergology & clinical immunology - 1 Jan 2000
Nieto A, Blanco Quirós A, Arranz E, Alonso Franch M, Garrote J A, Calvo C
Abstract excerpt
The familial incidence of celiac disease (CD) confirms its genetic basis, although acquired factors are also involved. Many authors have reported a linkage between celiac disease and HLA antigens, but there are differences which depend on geographical areas, and nowadays the study must be done at the genetic level. Thirty-eight celiac children and 52 normal controls were included in this study. All individuals...
Topics
- Adolescent
- Adult
- Alleles
- Celiac Disease
- Child
- Child, Preschool
- Disease Susceptibility
- Female
- Genes, MHC Class II
- Genotype
- HLA-DQ Antigens
- HLA-DQ alpha-Chains