Article
Molecular characterization of HLA class II genes in celiac disease patients of Latin American Caucasian origin.
Tissue antigens - 1 Feb 1994
Herrera M, Theiler G, Augustovski F, Chertkoff L, Fainboim L, DeRosa S, Cowan E P, Satz M L
Abstract excerpt
In the present study, the polymorphic domain of HLA class II genes present in a pediatric population of Argentinian celiac disease patients was analyzed by hybridization to sequence-specific oligonucleotides and DNA sequencing. Sixteen out of 16 DR5/7 heterozygous patients bore the DQA1*0501 and DQB1*0201 alleles implicated in the DQ2 risk specificity. The second exon of DQA1, DQB1 and DRB1 genes from 2 DR5/7...
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