Article
Allelic loss from chromosome 11 in parathyroid tumors.
Cancer research - 15 Dec 1992
Friedman E, De Marco L, Gejman P V, Norton J A, Bale A E, Aurbach G D, Spiegel A M, Marx S J
Abstract excerpt
Parathyroid tumors may occur in a sporadic fashion or, more rarely, as part of a familial syndrome (such as familial multiple endocrine neoplasia type I). The MENI gene has been mapped by linkage analysis to chromosome 11 at band q11-q13, and presumably acts as a tumor suppressor gene. In the present study, which is an extension of our previous studies, we examined 41 parathyroid tumors from patients with...
Topics
- Adenoma
- Alleles
- Chromosome Deletion
- Chromosomes, Human, Pair 11
- Humans
- Multiple Endocrine Neoplasia
- Parathyroid Glands
- Parathyroid Neoplasms