Article
Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients.
Cancer research - 15 Nov 1996
Lubensky I A, Debelenko L V, Zhuang Z, Emmert-Buck M R, Dong Q, Chandrasekharappa S, Guru S C, Manickam P, Olufemi S E, Marx S J, Spiegel A M, Collins F S, Liotta L A
Abstract excerpt
Familial multiple endocrine neoplasia type 1 is an autosomal dominant hereditary disorder characterized by multiple parathyroid, pancreatic, duodenal, and pituitary tumors. The parathyroid tumors may arise as diffuse areas of hyperplasia, whereas the pancreatic and duodenal tumors usually form as...
Topics
- Adult
- Alleles
- Chromosomes, Human, Pair 11
- Dosage Compensation, Genetic
- Female
- Gene Deletion
- Humans
- Male
- Middle Aged
- Multiple Endocrine Neoplasia Type 1
